Scratching activity and scoliosis (spine curvature) are also common manifestations. Some dogs will develop clinical signs of spinal cord dysfunction (myelopathy), usually in the cervical (neck) spinal cord region. This can be manifested by difficulty walking in all four limbs. In some cases, dogs with cervical myelopathy due to syringomyelia will develop a condition called central cord syndrome. In this scenario, the thoracic limbs are severely compromised, but the pelvic limbs are functioning normally or nearly so.